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five–4 μmol/L assortment,[156][157] the concentration of serotonin in synaptic vesicles was measured at 270 mM.[182] pursuing vesicular launch, the ensuing concentration of serotonin within the synaptic cleft, to which serotonin receptors are exposed, is estimated to generally be about 300 μmol/L. Consequently, while in vitro receptor binding